{"id":2398,"date":"2023-01-27T11:32:20","date_gmt":"2023-01-27T11:32:20","guid":{"rendered":"https:\/\/cbdoileurope.com\/water-soluble-cbd-an-in-depth-look-into-water-soluble-technologies\/"},"modified":"2024-08-22T13:15:28","modified_gmt":"2024-08-22T13:15:28","slug":"water-soluble-cbd-an-in-depth-look-into-water-soluble-technologies","status":"publish","type":"post","link":"https:\/\/cbdoileurope.com\/nl\/wateroplosbare-cbd-een-diepgaande-blik-op-wateroplosbare-technologieen\/","title":{"rendered":"In water oplosbare CBD - Een diepgaande blik op in water oplosbare technologie\u00ebn"},"content":{"rendered":"<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-black-color has-text-color has-link-color wp-elements-7a52668641dd81f64c201cff2d9f296c\"><strong>In water oplosbare CBD wordt steeds populairder als toegevoegd ingredi\u00ebnt aan CBD tincturen, capsules, edibles, dranken en topische cosmetica. Het komt voor in vele vormen, zowel vloeibaar als in poedervorm, en wordt op verschillende manieren gemaakt. In dit artikel worden de belangrijkste soorten in water oplosbare CBD beschreven, evenals de technische en wettelijke overwegingen die je in acht moet nemen bij het ontwikkelen van een product dat in water oplosbare CBD gebruikt.<\/strong><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Is CBD (Cannabidiol) oplosbaar in water?<\/h2>\n\n\n\n<p>CBD is hydrofoob, wat betekent dat het onoplosbaar is in water.<br>Om afscheiding van de olieachtige verbindingen in producten op waterbasis te voorkomen, is het nodig om een micro-inkapseling van het CBD-extract of CBD-isolaat te maken die compatibel is met water.<\/p>\n\n\n\n<p>Er zijn verschillende technologie\u00ebn beschikbaar en ze hebben allemaal hun eigen voor- en nadelen. We zijn voortdurend op zoek naar betere technologie\u00ebn, zorgen ervoor dat ze uitstekend zijn en kunnen profiteren van schaalvoordelen, want dat is wat onze klanten nodig hebben om deze nieuwe producten succesvol op de markt te brengen.<\/p>\n\n\n\n<p>Dit artikel bespreekt deze methode en de andere veelgebruikte methoden om een in water oplosbaar product te maken.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Verschillende soorten in water oplosbare CBD<\/h2>\n\n\n\n<p>Er zijn vijf hoofdmethoden om CBD-producten te maken die oplosbaar zijn in water<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Nano-emulgering<\/li>\n\n\n\n<li>Micelle<\/li>\n\n\n\n<li>Liposoom<\/li>\n\n\n\n<li>Gestabiliseerde ophanging<\/li>\n\n\n\n<li>Verestering<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Nano-emulgering<\/h2>\n\n\n\n<p>Nano-emulsies zijn emulsies van nanogrootte die worden gemaakt om de afgifte van actieve farmaceutische ingredi\u00ebnten te verbeteren. Dit zijn thermodynamisch stabiele isotrope systemen waarin twee niet-mengbare vloeistoffen worden gemengd tot een enkele fase door middel van een emulgeermiddel.<\/p>\n\n\n\n<p>Bij het maken van nano-emulge CBD wordt de CBD opgelost in een dragerolie die vloeibaar blijft bij een breed temperatuurbereik. Vervolgens wordt het gemengd met een emulgator die ook wel een oppervlakteactieve stof wordt genoemd. Deze werken op het grensvlak van de olie en het water om de druppel te stabiliseren. Deze oliefase wordt toegevoegd aan water en gemengd tot een grove emulsie (gestabiliseerde druppels olie gedispergeerd in water). De grove emulsie wordt vervolgens nano-emulgeerd met een emulgator onder hoge druk om zeer kleine druppeltjes te maken (~250nm) die langdurig stabiel zijn zonder te agglomereren (recombineren), te schuimen (naar boven drijven) of te sedimenteren (naar de bodem zinken).<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Nano-Emulsified-Water-Soluble-CBD-CBD-Oil-Europe-v1.2.webp\" alt=\"\" class=\"wp-image-17984\" srcset=\"https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Nano-Emulsified-Water-Soluble-CBD-CBD-Oil-Europe-v1.2.webp 800w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Nano-Emulsified-Water-Soluble-CBD-CBD-Oil-Europe-v1.2-300x225.webp 300w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Nano-Emulsified-Water-Soluble-CBD-CBD-Oil-Europe-v1.2-768x576.webp 768w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Nano-Emulsified-Water-Soluble-CBD-CBD-Oil-Europe-v1.2-360x270.webp 360w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Nano-Emulsified-Water-Soluble-CBD-CBD-Oil-Europe-v1.2-600x450.webp 600w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Micelle<\/h2>\n\n\n\n<p>A <span style=\"text-decoration: underline;\"><a href=\"https:\/\/en.wikipedia.org\/wiki\/Micelle\" data-type=\"link\" data-id=\"https:\/\/en.wikipedia.org\/wiki\/Micelle\" target=\"_blank\" rel=\"noreferrer noopener\">Micelle<\/a><\/span> is een kleine bol die bestaat uit 'oppervlakteactieve stoffen', kleine moleculen die 'amfifiel' zijn (ze hebben een waterminnende kop maar een waterafstotende staart). Door deze eigenschappen vormen ze microscopische belletjes die een andere (vettige) verbinding kunnen bevatten. Op deze manier ingekapseld kunnen de CBD-moleculen gelijkmatig door het water worden verspreid.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Micelle-Water-Soluble-CBD-CBD-Oil-Europe-.webp\" alt=\"\" class=\"wp-image-17985\" srcset=\"https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Micelle-Water-Soluble-CBD-CBD-Oil-Europe-.webp 800w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Micelle-Water-Soluble-CBD-CBD-Oil-Europe--300x225.webp 300w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Micelle-Water-Soluble-CBD-CBD-Oil-Europe--768x576.webp 768w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Micelle-Water-Soluble-CBD-CBD-Oil-Europe--360x270.webp 360w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Micelle-Water-Soluble-CBD-CBD-Oil-Europe--600x450.webp 600w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Liposoom<\/h2>\n\n\n\n<p>A <span style=\"text-decoration: underline;\"><a href=\"https:\/\/en.wikipedia.org\/wiki\/Liposome\" data-type=\"link\" data-id=\"https:\/\/en.wikipedia.org\/wiki\/Liposome\" target=\"_blank\" rel=\"noreferrer noopener\">liposoom<\/a><\/span> is vergelijkbaar met een micel, met als belangrijkste verschil dat een liposoombel is opgebouwd uit 2 lagen oppervlakte-actieve stoffen. Tussen de twee lagen kunnen vetachtige verbindingen worden opgeslagen, waarbij de hydrofobe staarten van de oppervlakteactieve stoffen naar elkaar toe gericht zijn.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Liposomal-Water-Soluble-CBD-CBD-Oil-Europe.webp\" alt=\"\" class=\"wp-image-17986\" srcset=\"https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Liposomal-Water-Soluble-CBD-CBD-Oil-Europe.webp 800w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Liposomal-Water-Soluble-CBD-CBD-Oil-Europe-300x225.webp 300w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Liposomal-Water-Soluble-CBD-CBD-Oil-Europe-768x576.webp 768w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Liposomal-Water-Soluble-CBD-CBD-Oil-Europe-360x270.webp 360w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Liposomal-Water-Soluble-CBD-CBD-Oil-Europe-600x450.webp 600w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Gestabiliseerde ophanging<\/h2>\n\n\n\n<p>In gestabiliseerde suspensie is CBD aanwezig in water als een zwevende vaste stof van nanogrootte. Het wordt verder gestabiliseerd met behulp van een paar verschillende technieken. Ladingsstabilisatie: Een negatief of positief geladen chemische stof die zich associeert met de CBD-deeltjes, waardoor wordt voorkomen dat ze samenklonteren tot grotere deeltjes.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Water-Soluble-CBD-Steric-Stabilization-and-Elecrostatic-Stabilization-CBD-Oil-Europe.webp\" alt=\"\" class=\"wp-image-17988\" srcset=\"https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Water-Soluble-CBD-Steric-Stabilization-and-Elecrostatic-Stabilization-CBD-Oil-Europe.webp 800w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Water-Soluble-CBD-Steric-Stabilization-and-Elecrostatic-Stabilization-CBD-Oil-Europe-300x225.webp 300w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Water-Soluble-CBD-Steric-Stabilization-and-Elecrostatic-Stabilization-CBD-Oil-Europe-768x576.webp 768w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Water-Soluble-CBD-Steric-Stabilization-and-Elecrostatic-Stabilization-CBD-Oil-Europe-360x270.webp 360w, https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/11\/Water-Soluble-CBD-Steric-Stabilization-and-Elecrostatic-Stabilization-CBD-Oil-Europe-600x450.webp 600w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Verestering<\/h2>\n\n\n\n<p>CBD kan chemisch worden gemodificeerd om esters te vormen, waardoor de oplosbaarheid in water toeneemt. Deze techniek wordt vaak gebruikt voor farmaceutische actieve ingredi\u00ebnten, maar vereist een aanzienlijke chemische behandeling van de basismolecule, samen met verdere extractie en zuivering om resterende chemicali\u00ebn te verwijderen. Veresterde geneesmiddelen worden vaak \"prodrugs\" genoemd, omdat de actieve vorm ontstaat wanneer de ester verloren gaat. Veresterd CBD opgelost in water vormt een oplossing.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">In water oplosbare CBD-vloeistoffen<\/h2>\n\n\n\n<p>In water oplosbare CBD-vloeistoffen kunnen worden ingekapseld in zachte gels of harde capsules. De aard van hun formulering betekent dat ze een hogere absorptiesnelheid hebben dan conventionele CBD-producten, omdat de nanodeeltjes direct kunnen worden opgenomen zonder door de lever te worden gemetaboliseerd. Dit betekent dat je dezelfde effecten krijgt door minder product te gebruiken. In water oplosbare producten die op deze manier worden gebruikt, vallen onder de nieuwe regelgeving voor voedingsmiddelen.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">In water oplosbaar CBD poeder<\/h2>\n\n\n\n<p>Bij het kiezen van een wateroplosbaar CBD-poeder moet de belangrijkste overweging zijn hoe het door je klant zal worden ingenomen. Wordt het gemengd en meteen geconsumeerd, of moet het product oplossen en in oplossing blijven zonder los te komen.<\/p>\n\n\n\n<p>CBD-poeders kunnen perfect zijn om te mengen in eiwitrepen of om direct op te lossen in een energierecuperatiedrank voorafgaand aan consumptie en voor de productie van slurries, halfvaste en vaste producten.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">In water oplosbare CBD voor drankjes en dranken<\/h2>\n\n\n\n<p>Bij het kiezen van een wateroplosbaar product voor dranken moet je er rekening mee houden of de drank koolzuurhoudend zal zijn en wat het Ph-niveau van de drank is. Producten met een laag Ph-gehalte kunnen de emulsie verstoren.  Ook het type verpakking dat wordt gebruikt kan van invloed zijn op bepaalde soorten in water oplosbare CBD.<\/p>\n\n\n\n<p>Als je een wateroplosbaar CBD-water maakt, moet je ook rekening houden met de smaak van de CBD. Moet je andere smaakstoffen toevoegen om dit te maskeren? Wij kunnen gespecialiseerde nano-formuleringen leveren die smaakloos en helder zijn en ideaal voor het maken van CBD water.<\/p>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>In water oplosbare CBD wordt steeds populairder als toegevoegd ingredi\u00ebnt aan CBD tincturen, capsules, edibles, dranken en topische cosmetica. Het komt voor in vele vormen, zowel vloeibaar als in poedervorm, en wordt op verschillende manieren gemaakt. In dit artikel worden de belangrijkste soorten in water oplosbare CBD beschreven, evenals de technische en wettelijke [...]<\/p>","protected":false},"author":1,"featured_media":17849,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[28],"tags":[],"class_list":["post-2398","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-business"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.2 (Yoast SEO v23.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Water Soluble CBD - An in depth look into water soluble technologies - CBD Oil Europe<\/title>\n<meta name=\"description\" content=\"Water soluble CBD - Technical and regulatory considerations you should take when developing a product using water soluble CBD.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cbdoileurope.com\/nl\/wateroplosbare-cbd-een-diepgaande-blik-op-wateroplosbare-technologieen\/\" \/>\n<meta property=\"og:locale\" content=\"nl_NL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Water Soluble CBD - An in depth look into water soluble technologies\" \/>\n<meta property=\"og:description\" content=\"Water soluble CBD - Technical and regulatory considerations you should take when developing a product using water soluble CBD.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cbdoileurope.com\/nl\/wateroplosbare-cbd-een-diepgaande-blik-op-wateroplosbare-technologieen\/\" \/>\n<meta property=\"og:site_name\" content=\"CBD Oil Europe\" \/>\n<meta property=\"article:published_time\" content=\"2023-01-27T11:32:20+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-08-22T13:15:28+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cbdoileurope.com\/wp-content\/uploads\/2023\/01\/Water-Soluble-CBD-An-in-depth-look-into-water-soluble-technologies-01.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1440\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Laurens van Dijk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Geschreven door\" \/>\n\t<meta name=\"twitter:data1\" content=\"Laurens van Dijk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Geschatte leestijd\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/cbdoileurope.com\/water-soluble-cbd-an-in-depth-look-into-water-soluble-technologies\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/cbdoileurope.com\/water-soluble-cbd-an-in-depth-look-into-water-soluble-technologies\/\"},\"author\":{\"name\":\"Laurens van Dijk\",\"@id\":\"https:\/\/cbdoileurope.com\/#\/schema\/person\/95c9aa04834e50d8416ac20cf17a2b52\"},\"headline\":\"Water Soluble CBD &#8211; 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